Article
An update on the genetics of colorectal cancer.
Human molecular genetics - 1 Oct 2004
Kemp Zoe, Thirlwell Cristina, Sieber Oliver, Silver Andrew, Tomlinson Ian
Abstract excerpt
Colorectal carcinoma (CRC) remains a frequent cause of cancer-associated mortality in the UK and still has a relatively poor outcome. Single gene defects account for up to 2-6% of cases, but twin studies suggest a hereditary component in 35%. CRC represents a paradigm for cancer genetics. Almost all the major-gene influences on CRC have been identified, and the identification of the remaining susceptibility...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.