Article
Proviral HIV-DNA predicts viral rebound and viral setpoint after structured treatment interruptions.
AIDS (London, England) - 24 Sept 2004
Yerly Sabine, Günthard Huldrych F, Fagard Catherine, Joos Béda, Perneger Thomas V, Hirschel Bernard, Perrin Luc
Abstract excerpt
In HIV-1-infected patients with long-term undetectable viraemia on highly active antiretroviral treatment (HAART), we found that pre-HAART plasma viraemia and the baseline proviral DNA level were significantly associated with the viraemia setpoint during scheduled treatment interruptions. In long-term treated patients, pre-HAART viraemia may not be available, and in these circumstances proviral DNA, measured at...
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