Article
Factor V G1691A, prothrombin G20210A, and methylenetetrahydrofolate reductase [MTHFR] C677T gene polymorphism in angiographically documented coronary artery disease.
Journal of thrombosis and thrombolysis - 1 Jun 2004
Almawi Wassim Y, Ameen Ghada, Tamim Hala, Finan Ramzi R, Irani-Hakime Noha
Abstract excerpt
BACKGROUND: Single point mutations in the genes coding for factor V [G1691A; Leiden], prothrombin [PRT; G20210A], and methylenetetrahydrofolate reductase [MTHFR, C677T] were shown to be major inherited predisposing factors for venous thromboembolism. However, their contribution in the development of coronary artery disease [CAD] remains controversial. The aim of the study was to examine the association of these...
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