Article
Factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations are not associated with chronic limb ischemia: the Linz Peripheral Arterial Disease (LIPAD) study.
Journal of vascular surgery - 1 May 2005
Mueller Thomas, Marschon Renate, Dieplinger Benjamin, Haidinger Dieter, Gegenhuber Alfons, Poelz Werner, Webersinke Gerald, Haltmayer Meinhard
Abstract excerpt
OBJECTIVE: Factor V G1691A (Leiden), prothrombin G20210A, and methylenetetrahydrofolate reductase (MTHFR) C677T mutations are considered risk factors for venous thromboembolism. It remains to be characterized whether the presence of these relatively common mutations poses a risk for peripheral arterial disease (PAD). Therefore, we intended to test, by conducting a case-control study, the hypothesis that PAD was...
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