Article
Analysis of microenvironmental factors contributing to basement membrane assembly and normalized epidermal phenotype.
The Journal of investigative dermatology - 1 Jun 2003
Andriani Frank, Margulis Alexander, Lin Ning, Griffey Sy, Garlick Jonathan A
Abstract excerpt
To understand further the role of the dynamic interplay between keratinocytes and stromal components in the regulation of the growth, differentiation, morphogenesis, and basement membrane assembly of human stratified squamous epithelium, we have generated novel, three-dimensional organotypic cultures in which skin keratinocytes were grown in the absence or presence of pre-existing basement membrane components...
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