Article
Reactivity of monoclonal antibody 1E5.B5 with a novel phenotypic marker expressed on a murine natural suppressor cell subset.
Hybridoma - 1 Apr 1992
Hoskin D W, Brooks-Kaiser J C, Kaiser M, Murgita R A
Abstract excerpt
Natural suppressor (NS) cells are antigen-nonspecific, MHC-independent immunoregulatory cells that are typically found in murine bone marrow (BM), newborn (NB) mouse spleen, and in splenic tissue of adult mice during pregnancy and following cyclophosphamide (CY) treatment. There has been a pressing need for the development of NS cell-specific monoclonal antibodies (mAb) since NS cells are generally described as...
Topics
- Animals
- Antibodies, Monoclonal
- Antibody Specificity
- Antigens, Differentiation
- Cytotoxicity, Immunologic
- Female
- Hybridomas
- Mice
- Mice, Inbred CBA
- Mice, Inbred DBA
- Phenotype