Article
Pregnancy-associated suppressor cells in mice: functional characteristics of CD3+4-8-45R+ T cells with natural suppressor activity.
Journal of reproductive immunology - 1 Mar 1992
Brooks-Kaiser J C, Murgita R A, Hoskin D W
Abstract excerpt
Natural suppressor (NS) cells are MHC-unrestricted regulatory cells with non-specific inhibitory activity for immune responses. In adult mice, NS cells are characteristically found in bone marrow and in splenic tissue following total lymphoid irradiation and cyclophosphamide treatments. Recently, we have shown that the spleens of pregnant mice harbour a population of lymphocytes which resemble NS cells in terms...
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