Pregnancy-associated suppressor cells in mice: functional characteristics of CD3+4-8-45R+ T cells with natural suppressor activity.

doi:10.1016/0165-0378(92)90018-y

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Article

Pregnancy-associated suppressor cells in mice: functional characteristics of CD3+4-8-45R+ T cells with natural suppressor activity.

Journal of reproductive immunology - 1 Mar 1992

Brooks-Kaiser J C, Murgita R A, Hoskin D W

Abstract excerpt

Natural suppressor (NS) cells are MHC-unrestricted regulatory cells with non-specific inhibitory activity for immune responses. In adult mice, NS cells are characteristically found in bone marrow and in splenic tissue following total lymphoid irradiation and cyclophosphamide treatments. Recently, we have shown that the spleens of pregnant mice harbour a population of lymphocytes which resemble NS cells in terms...

Topics

Animals
Antigens, CD
Antigens, Differentiation, T-Lymphocyte
CD3 Complex
CD4 Antigens
Female
Histocompatibility Antigens
Leukocyte Common Antigens
Lymphocyte Culture Test, Mixed
Male
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred CBA

Mice, Inbred DBA

Phenotype

Pregnancy

Pregnancy, Animal

Receptors, Antigen, T-Cell

Receptors, Mitogen

Source

Open in PubMed

Identifiers

PMID: 1532207
DOI: 10.1016/0165-0378(92)90018-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1532207-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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