Phantom encodes the 25-hydroxylase of Drosophila melanogaster and Bombyx mori: a P450 enzyme critical in ecdysone biosynthesis.

doi:10.1016/j.ibmb.2004.06.009

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Article

Phantom encodes the 25-hydroxylase of Drosophila melanogaster and Bombyx mori: a P450 enzyme critical in ecdysone biosynthesis.

Insect biochemistry and molecular biology - 1 Sept 2004

Warren James T, Petryk Anna, Marqués Guillermo, Parvy Jean-Philippe, Shinoda Tetsuro, Itoyama Kyo, Kobayashi Jun, Jarcho Michael, Li Yutai, O'Connor Michael B, Dauphin-Villemant Chantal, Gilbert Lawrence I

Abstract excerpt

We have reported recently the identification and characterization of the last three mitochondrial cytochrome P450 enzymes (CYP) controlling the biosynthesis of 20-hydroxyecdysone, the molting hormone of insects. These are encoded by the following genes: disembodied (dib, Cyp302a1, the 22-hydroxylase); shadow (sad, Cyp315a1, the 2-hydroxylase); and shade (shd, Cyp314a1, the 20-hydroxylase). Employing similar gene...

Topics

Amino Acid Sequence
Animals
Bombyx
DNA, Complementary
Drosophila Proteins
Drosophila melanogaster
Exocrine Glands
Gene Expression Regulation, Developmental
Gene Expression Regulation, Enzymologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mixed Function Oxygenases

Molecular Sequence Data

Phenotype

Reverse Transcriptase Polymerase Chain Reaction

Sequence Homology, Amino Acid

Transfection

Source

Open in PubMed

Identifiers

PMID: 15350618
DOI: 10.1016/j.ibmb.2004.06.009

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