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Article

Coactivators p300 and PCAF physically and functionally interact with the foamy viral trans-activator.

BMC molecular biology - 6 Sept 2004

Bannert Helmut, Muranyi Walter, Ogryzko Vasily V, Nakatani Yoshihiro, Flügel Rolf M

Abstract excerpt

BACKGROUND: Foamy virus Bel1/Tas trans-activators act as key regulators of gene expression and directly bind to Bel1 response elements (BRE) in both the internal and the 5'LTR promoters leading to strong transcriptional trans-activation. Cellular coactivators interacting with Bel1/Tas are unknown to date. RESULTS: Transient expression assays, co-immunoprecipitation experiments, pull-down assays, and Western blot...

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PMID: 15350211
DOI: 10.1186/1471-2199-5-16
PMCID: PMC517496

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Coactivators p300 and PCAF physically and functionally interact with the foamy viral trans-activator.PMID 15350211Read ↗

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