Article
The human foamy virus internal promoter is required for efficient gene expression and infectivity.
Virology - 10 Jan 1995
Löchelt M, Yu S F, Linial M L, Flügel R M
Abstract excerpt
The human foamy or spumaretrovirus (HFV) is a complex retrovirus that codes for the three retroviral genes gag, pol, and env and the regulatory and accessory bel genes. A particular feature of HFV gene expression was recently described: not only does the HFV provirus contain the classical retroviral long terminal repeat promoter, a second functionally active promoter is present in the env gene upstream of the bel...
Topics
- Animals
- Base Sequence
- Cell Line
- DNA Primers
- Gene Expression Regulation, Viral
- Genetic Complementation Test
- Humans
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- Proviruses