Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

AZF and DAZ gene copy-specific deletion analysis in maturation arrest and Sertoli cell-only syndrome

7 Sept 2004

Abstract excerpt

Deletions of the AZFc region in Yq11.2, which include the DAZ gene family, are responsible for most cases of male infertility and were associated with severe oligozoospermia and also with a variable testicular pathology. To uncover the functional contribution of DAZ to human spermatogenesis, a DAZ gene copy-specific deletion analysis was previously established and showed that DAZ1/DAZ2 deletions associate with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Sexual Differentiation and Disorders
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15347736
DOI: 10.1093/molehr/gah104

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

AZF and DAZ gene copy-specific deletion analysis in maturation arrest and Sertoli cell-only syndromePMID 15347736Read ↗

High frequency of DAZ1/DAZ2 gene deletions in patients with severe oligozoospermiaSemantic proximity Read ↗

Human male infertility and Y chromosome deletions: role of the AZF-candidate genes DAZ, RBM and DFFRY.Semantic proximity Read ↗

Male Infertility Caused by a de Novo Partial Deletion of the DAZ Cluster on the Y Chromosome1Semantic proximity Read ↗

Sons conceived by assisted reproduction techniques inherit deletions in the azoospermia factor (AZF) region of the Y chromosome and the DAZ gene copy number.Semantic proximity Read ↗

Azoospermic men with deletion of the DAZ gene cluster are capable of completing spermatogenesis: fertilization, normal embryonic development and pregnancy occur when retrieved testicular spermatozoa are used for intracytoplasmic sperm injectionSemantic proximity Read ↗

Genetic aspects of human male infertility: the frequency of chromosomal abnormalities and Y chromosome microdeletions in severe male factor infertility.Semantic proximity Read ↗

Analysis of the DAZ gene family in cryptorchidism and idiopathic male infertility.Semantic proximity Read ↗

Y-chromosome AZFc structural architecture and relationship to male fertility.Semantic proximity Read ↗

Association of partial AZFc region deletions with spermatogenic impairment and male infertility.Semantic proximity Read ↗

Screening for AZF Deletion in a Large Series of Severely Impaired Spermatogenesis PatientsSemantic proximity Read ↗

High deletion frequency of the complete AZFa sequence in men with Sertoli-cell-only syndromeSemantic proximity Read ↗

Y-chromosome microdeletion and phenotype in cytogenetically normal men with idiopathic azoospermia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.