Article
Human male infertility and Y chromosome deletions: role of the AZF-candidate genes DAZ, RBM and DFFRY.
Human reproduction (Oxford, England) - 1 Jul 1999
Ferlin A, Moro E, Garolla A, Foresta C
Abstract excerpt
Microdeletions in Yq11 overlapping three distinct 'azoospermia factors' (AZFa-c) represent the aetiological factor of 10-15% of idiopathic azoospermia and severe oligozoospermia, with higher prevalence in more severe testiculopathies, such as Sertoli cell-only syndrome. Using a PCR-based screening, we analysed Yq microdeletions in 180 infertile patients affected by idiopathic Sertoli cell-only syndrome and...
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