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Article

Role of N-linked glycosylation in the secretion and activity of endothelial lipase.

Journal of lipid research - 1 Nov 2004

Miller Gwen C, Long Christopher J, Bojilova Ekaterina D, Marchadier Dawn, Badellino Karen O, Blanchard Nadine, Fuki Ilia V, Glick Jane M, Rader Daniel J

Abstract excerpt

Human endothelial lipase (EL), a member of the triglyceride lipase gene family, has five potential N-linked glycosylation sites, two of which are conserved in both lipoprotein lipase and hepatic lipase. Reduction in molecular mass of EL after treatment with glycosidases and after treatment of EL-expressing cells with the glycosylation inhibitor tunicamycin demonstrated that EL is a glycosylated protein. Each...

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PMID: 15342690
DOI: 10.1194/jlr.M400162-JLR200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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