Article
Tumor necrosis factor promoter haplotype associated with schizophrenia reveals a linked locus on 1q44.
Molecular psychiatry - 1 Apr 2005
Saviouk V, Chow E W C, Bassett A S, Brzustowicz L M
Abstract excerpt
Using restriction fragment length polymorphism and pyrosequencing methods, we genotyped two TNFA gene promoter SNPs (-G308A, -G238A) and analyzed the haplotype structure in 24 Canadian families of primarily Celtic origin. Our results demonstrate that after correction for multiple testing based on simulations of 10 000 replicates of unlinked/unassociated data, there is evidence for association (P=0.026) of a...
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