Human Langerhans cells express a novel form of the leukocyte common antigen (CD45).

doi:10.1046/j.1523-1747.1998.00355.x

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Article

Human Langerhans cells express a novel form of the leukocyte common antigen (CD45).

The Journal of investigative dermatology - 1 Oct 1998

Wood G S, Szwejbka P, Schwandt A

Abstract excerpt

CD45 is a family of transmembrane glycoproteins that function as protein tyrosine phosphatases. All isoforms exhibit common CD45 epitopes, whereas the restricted CD45 epitopes (RA, RB, and RO) are each limited to one or more isoforms. In prior studies, we showed that human Langerhans cells in nor...

Topics

Epitopes
Exons
Genetic Variation
Humans
Langerhans Cells
Leukocyte Common Antigens
Protein Isoforms
Transcription, Genetic

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