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Article

HNPCC and sporadic MSI-H colorectal cancer: a review of the morphological similarities and differences.

Familial cancer - 1 Jan 2004

Jass Jeremy R

Abstract excerpt

Morphological features may serve as diagnostically useful markers of colorectal cancer (CRC) with the microsatellite instability-high (MSI-H) phenotype. The most important of these are lymphocytic infiltration, mucin secretion and poor differentiation. These features are apparent in both sporadic MSI-H CRC and CRC occurring in the context of hereditary non-polyposis colorectal cancer (HNPCC). There is now strong...

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Identifiers

PMID: 15340259
DOI: 10.1023/B:FAME.0000039849.86008.b7

Genes

APC
BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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