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Different Effects ofCSAandCSBDeficiency on Sensitivity to Oxidative DNA Damage

31 Aug 2004

Abstract excerpt

Mutations in the CSA and CSB genes cause Cockayne syndrome, a rare inherited disorder characterized by UV sensitivity, severe neurological abnormalities, and progeriod symptoms. Both gene products function in the transcription-coupled repair (TCR) subpathway of nucleotide excision repair (NER), providing the cell with a mechanism to remove transcription-blocking lesions from the transcribed strands of actively...

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PMID: 15340056
DOI: 10.1128/mcb.24.18.7941-7948.2004

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Different Effects ofCSAandCSBDeficiency on Sensitivity to Oxidative DNA DamagePMID 15340056Read ↗

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