Article
Global genome repair of 8-oxoG in hamster cells requires a functional CSB gene product.
Oncogene - 16 May 2002
Sunesen Morten, Stevnsner Tinna, Brosh Robert M, Dianov Grigory L, Bohr Vilhelm A
Abstract excerpt
Cockayne syndrome (CS) is an autosomal recessive human disease characterized by UV-sensitivity as well as neurological and developmental abnormalities. Two complementation groups have been established, designated CS-A and CS-B. Traditionally, CSA and CSB have been ascribed a function in the transcription-coupled repair (TCR) pathway of nucleotide excision repair (NER) that efficiently removes bulky lesions from...
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