Article
Essential motifs in the 3' untranslated region required for retrotransposition and the precise start of reverse transcription in non-long-terminal-repeat retrotransposon SART1.
Molecular and cellular biology - 1 Sept 2004
Osanai Mizuko, Takahashi Hidekazu, Kojima Kenji K, Hamada Mitsuhiro, Fujiwara Haruhiko
Abstract excerpt
Non-long-terminal-repeat (non-LTR) retrotransposons amplify their copies by reverse transcribing mRNA from the 3' end, but the initial processes of reverse transcription are still unclear. We have shown that a telomere-specific non-LTR retrotransposon of the silkworm, SART1, requires the 3' untranslated region (3' UTR) for retrotransposition. With an in vivo retrotransposition assay, we identified several novel...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.