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Article

Vascular endothelial growth factor and nephrin interact and reduce apoptosis in human podocytes.

American journal of physiology. Renal physiology - 1 Jan 2005

Foster Rebecca R, Saleem Moin A, Mathieson Peter W, Bates David O, Harper Steven J

Abstract excerpt

Vascular endothelial growth factor (VEGF) is anti-cytotoxic in podocytes. Moreover, it has been suggested that nephrin, a cell adhesion molecule of the podocyte slit diaphragm, can contribute to antiapoptotic mechanisms in these cells. We therefore investigated whether VEGF signals to reduce apoptosis and the role of nephrin in this survival mechanism. Flow cytometry showed that podocytes with nephrin mutations...

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Source

Identifiers

PMID: 15339792
DOI: 10.1152/ajprenal.00146.2004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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