Article
A Conditionally Immortalized Human Podocyte Cell Line Demonstrating Nephrin and Podocin Expression
1 Mar 2002
Abstract excerpt
Recent molecular insights have established the podocyte as a key component of the glomerular filtration barrier, and hence an important common pathway in proteinuric diseases. A conditionally immortalized human podocyte cell line has been developed by transfection with the temperature-sensitive SV40-T gene. These cells proliferate at the "permissive" temperature (33 degrees C). After transfer to the...
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