Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic analysis of the glutathione s-transferase genes MGST1, GSTM3, GSTT1, and GSTM1 in patients with hereditary pancreatitis.

Journal of gastroenterology - 1 Aug 2004

Schneider Alexander, Tögel Sandra, Barmada M Michael, Whitcomb David C

Abstract excerpt

BACKGROUND: Specific mutations in the cationic trypsinogen gene ( PRSS1) are disease-causing in patients with hereditary pancreatitis, but the genetic background still remains mysterious in about 40% of patients with the disease. It has been suggested that oxidative stress contributes to pancreatic damage. The glutathione s-transferases (GSTs) represent major detoxification enzymes that protect cells from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Disease
Share to Glutathione Transferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Open Reading Frames

Share to Oxidative Stress

Share to Pancreatitis

Share to Reference Values

Share to Trypsin

Share to Trypsinogen

Source

Identifiers

PMID: 15338373
DOI: 10.1007/s00535-004-1389-7

Genes

GSTM1
GSTT1
GSTM3
MGST1
PRSS1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Genetic analysis of the glutathione s-transferase genes MGST1, GSTM3, GSTT1, and GSTM1 in patients with hereditary pancreatitis.PMID 15338373Read ↗

Glutathione S-transferase M1 and glutathione S-transferase T1 genotype in chronic pancreatitis: a meta-analysis.Semantic proximity Read ↗

Genetic Susceptibility in Acute Pancreatitis: Genotyping of GSTM1, GSTT1, GSTP1, CASP7, CASP8, CASP9, CASP10, LTA, TNFRSF1B, and TP53 Gene Variants.Semantic proximity Read ↗

Alpha1-antitrypsin genotypes in patients with chronic pancreatitis.Semantic proximity Read ↗

Analysis of the human pancreatic secretory trypsin inhibitor (PSTI) gene mutations in Japanese patients with chronic pancreatitis.Semantic proximity Read ↗

Complete analysis of the human mesotrypsinogen gene (PRSS3) in patients with chronic pancreatitis.Semantic proximity Read ↗

Functional polymorphisms of UDP-glucuronosyltransferases 1A1, 1A6 and 1A8 are not involved in chronic pancreatitis.Semantic proximity Read ↗

Glutathione S-transferase Mu null genotype affords protection against alcohol induced chronic pancreatitis.Semantic proximity Read ↗

Genetic analyses of heme oxygenase 1 (HMOX1) in different forms of pancreatitis.Semantic proximity Read ↗

Quantitative analysis of interindividual variation of glutathione S-transferase expression in human pancreas and the ambiguity of correlating genotype with phenotype.Semantic proximity Read ↗

Mutational analysis of the gene encoding the zymogen granule membrane glycoprotein 2 (GP2) in patients with chronic pancreatitis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.