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Article

CYP1A1, GSTM1 and GSTT1 genetic polymorphism is associated with susceptibility to polycystic ovaries in South Indian women.

Reproductive biomedicine online - 1 Aug 2004

Babu K Arvind, Rao K Lakshmi, Kanakavalli M K, Suryanarayana V V, Deenadayal Mamata, Singh Lalji

Abstract excerpt

Polymorphic variants in the phase I enzyme, cytochrome P450 gene, may lead to increased toxification, whereas polymorphisms in the phase II enzyme, glutathione S-transferase genes, may result in impaired detoxification. Alterations in the activities of phase I drug metabolizing enzymes and phase II detoxification enzymes may cause abnormal functioning and formation of follicular cysts in the ovaries and thus...

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Source

Identifiers

PMID: 15333250
DOI: 10.1016/s1472-6483(10)62129-3

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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