Article
Genetic association of phase I and phase II detoxification genes with recurrent miscarriages among North Indian women.
Molecular human reproduction - 1 Mar 2010
Parveen F, Faridi R M, Das V, Tripathi G, Agrawal S
Abstract excerpt
Allelic variants of the detoxification genes that have impaired biotransformation functions may increase susceptibility to reproductive toxicity leading to endometriosis, recurrent miscarriage (RM) or poor pregnancy outcome. In the present study, we have investigated CYP1A1, CYP2D6, GSTT1, GSTP1 and GSTM1, which are involved in the phase I and phase II detoxification systems, in relation to their role in the...
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