Article
Polymorphisms of the GSTT1 and GSTM1 genes in polycystic ovary syndrome.
Revista da Associacao Medica Brasileira (1992) - 1 Nov 2020
Azevedo Mariana Mendes Porto, Marqui Alessandra Bernadete Trovó de, Bacalá Bruna Tavares, Balarin Marly Aparecida Spadotto, Resende Elisabete Aparecida Mantovanni Rodrigues de, Lima Marco Fábio Prata, Gomes Mariana Kefalás de Oliveira, Cintra Mariangela Torreglosa Ruiz
Abstract excerpt
BACKGROUND: This study aimed to investigate the deletion polymorphisms of the genes of the glutathione S-transferase family GSTT1 and GSTM1 in patients with Polycystic Ovarian Syndrome (PCOS), comparing them with a control population. METHODS: Blood was collected from 219 women (110 with PCOS and 109 controls) and genomic DNA was extracted. For the analysis of polymorphisms, the technique used was multiplex PCR....
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