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Article

Molecular clock in neutral protein evolution.

BMC genetics - 27 Aug 2004

Wilke Claus O

Abstract excerpt

BACKGROUND: A frequent observation in molecular evolution is that amino-acid substitution rates show an index of dispersion (that is, ratio of variance to mean) substantially larger than one. This observation has been termed the overdispersed molecular clock. On the basis of in silico protein-evolution experiments, Bastolla and coworkers recently proposed an explanation for this observation: Proteins drift in...

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PMID: 15333142
DOI: 10.1186/1471-2156-5-25
PMCID: PMC517495

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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