Article
Increased cardiovascular risk in long-term hemodialysis patients carrying deletion allele of ACE gene polymorphism.
American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Sept 2004
Ishimitsu Toshihiko, Tsukada Kohju, Ohta Satoshi, Inada Hideki, Minami Junichi, Ono Hidehiko, Matsuoka Hiroaki
Abstract excerpt
BACKGROUND: Controversy continues about the relation of insertion (I)/deletion (D) polymorphism of the angiotensin-converting enzyme (ACE) gene to the genetic predisposition to develop such cardiovascular diseases as myocardial infarction, stroke, and other arteriosclerotic disorders. METHODS: To examine the relation of ACE gene polymorphism to risk for developing cardiovascular diseases in long-term hemodialysis...
Topics
- Aged
- Cardiovascular Diseases
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Middle Aged
- Peptidyl-Dipeptidase A
- Polymorphism, Genetic
- Proportional Hazards Models
- Prospective Studies
- Renal Dialysis