Article
Angiotensin-converting enzyme polymorphism in patients with terminal renal failure.
Journal of the American Society of Nephrology : JASN - 1 Feb 1996
Schmidt A, Kiener H P, Barnas U, Arias I, Illievich A, Auinger M, Graninger W, Kaider A, Mayer G
Abstract excerpt
An insertion/deletion polymorphism has been described for the gene that encodes the angiotensin-converting enzyme. The deletion allele is associated with higher angiotensin-converting enzyme plasma levels, which ultimately might lead to increased angiotensin II concentrations. Because angiotensin II is a mediator for progressive renal injury, this study determined the frequency of distribution of the...
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