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Article

Effects of the Delta67 complex of mutations in human immunodeficiency virus type 1 reverse transcriptase on nucleoside analog excision.

Journal of virology - 1 Sept 2004

Boyer Paul L, Imamichi Tomozumi, Sarafianos Stefan G, Arnold Edward, Hughes Stephen H

Abstract excerpt

Long-term use of combination therapy against human immunodeficiency virus type (HIV-1) provides strong selective pressure on the virus, and HIV-1 variants that are resistant to multiple inhibitors have been isolated. HIV-1 variants containing amino acid substitutions within the coding region of HIV-1 reverse transcriptase (RT), such as the 3'-azido-3'-deoxythymidine (AZT)-resistant variant AZT-R...

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Identifiers

PMID: 15331732
DOI: 10.1128/JVI.78.18.9987-9997.2004
PMCID: PMC515022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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