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Article

Prostaglandin E2 activates Src signaling in lung adenocarcinoma cell via EP3.

Cancer letters - 8 Oct 2004

Yamaki Tatsuya, Endoh Kiyoko, Miyahara Mituyoshi, Nagamine Isao, Thi Thu Huong Nguyen, Sakurai Hidetoshi, Pokorny Jan, Yano Tomohiro

Abstract excerpt

Accumulating evidence suggests that overproduction of prostaglandin (PG) E2 attributable to induction of cyclooxygenase-2 plays an important role in the development of lung adenocarcinoma. Recently, we have reported that a PGE2 receptor, EP3 is involved in appearance of malignant phenotype of a lung adenocarcinoma cell (A549 cell). In line with our previous study, here we investigated if Src signaling could be...

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Identifiers

PMID: 15331179
DOI: 10.1016/j.canlet.2004.04.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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