Article
Presence of apolipoprotein E epsilon4 allele predisposes to early onset of primary Sjogren's syndrome.
Rheumatology (Oxford, England) - 1 Dec 2004
Pertovaara M, Lehtimäki T, Rontu R, Antonen J, Pasternack A, Hurme M
Abstract excerpt
BACKGROUND: Apolipoprotein E (apoE) polymorphism plays a central role in lipid metabolism, but has recently also been suggested to regulate inflammation, as judged by levels of serum C-reactive protein (CRP). OBJECTIVE: To establish whether polymorphism of the apoE genes affects susceptibility to primary Sjogren's syndrome (pSS), degree of inflammation or age of onset of pSS. METHODS: ApoE genotype distribution...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.