Article
Apolipoprotein epsilon4 allele is associated with psoriasis severity.
Archives of dermatological research - 1 Mar 2010
Coto-Segura Pablo, Coto Eliecer, Alvarez Victoria, Morales Blanca, Soto-Sánchez Javier, Corao A I, Santos-Juanes Jorge
Abstract excerpt
Many reports provided strong evidence of the influence of genetic factors in the pathogenesis of psoriasis (Ps). A higher prevalence of lipid disorders in psoriatic patients has been reported. Because apolipoprotein E (apoE) is involved in lipid metabolism, APOE gene variants could be candidates to influence Ps-risk. However, data about the potential influence of the APOE genotypes in Ps are inconclusive. Our...
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