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Article

Biochemical analysis of respiratory function in cybrid cell lines harbouring mitochondrial DNA mutations.

The Biochemical journal - 1 Dec 2004

Pallotti Francesco, Baracca Alessandra, Hernandez-Rosa Evelyn, Walker Winsome F, Solaini Giancarlo, Lenaz Giorgio, Melzi D'Eril Gian Vico, Dimauro Salvatore, Schon Eric A, Davidson Mercy M

Abstract excerpt

We analysed key biochemical features that reflect the balance between glycolysis and glucose oxidation in cybrids (cytoplasmic hybrids) harbouring a representative sample of mitochondrial DNA point mutations and deletions. The cybrids analysed had the same 143B cell nuclear background and were isogenic for the mitochondrial background. The 143B cell line and its rho(0) counterpart were used as controls. All cells...

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Identifiers

PMID: 15324306
DOI: 10.1042/BJ20040561
PMCID: PMC1134112

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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