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Article

Growth phase regulation of flaA expression in Helicobacter pylori is luxS dependent.

Infection and immunity - 1 Sept 2004

Loh John T, Forsyth Mark H, Cover Timothy L

Abstract excerpt

LuxS plays a role in the synthesis of an extracellular signaling molecule, autoinducer 2 (AI-2). To analyze a possible role of AI-2 in regulating Helicobacter pylori gene expression, we constructed a panel of transcriptional reporter strains. We show that the expression of H. pylori flaA is growth phase dependent and that flaA transcription increases in association with increased culture density. Mutating the...

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Identifiers

PMID: 15322055
DOI: 10.1128/IAI.72.9.5506-5510.2004
PMCID: PMC517482

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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