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Effect of growth phase and acid shock on Helicobacter pylori cagA expression

1 Nov 1996

Abstract excerpt

Helicobacter pylori strains possessing cagA are associated with peptic ulceration. To understand the regulation of expression of cagA, picB, associated with interleukin-8 induction, and ureA, encoding the small urease subunit, we created gene fusions of cagA, ureA, and picB of strain 3401, using a promoterless reporter (xylE). Expression of XylE after growth in broth culture revealed that basal levels of...

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PMID: 8890198
DOI: 10.1128/iai.64.11.4501-4507.1996

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