Subgroups of Tcr alpha chains and correlation with T-cell function.

doi:10.1007/BF00166827

Back to search

Article

Subgroups of Tcr alpha chains and correlation with T-cell function.

Immunogenetics - 1 Jan 1992

Schiffer M, Kabat E A, Wu T T

Abstract excerpt

T-cell receptor (Tcr) alpha chains are classified into four subgroups (I, II, III, and miscellaneous) based on the amino acid residues at positions 61 and 62. Subgroup I has Gly Phe at these positions, subgroup II has Arg Phe, subgroup III has Arg Leu, and subgroup miscellaneous has several other...

Topics

Amino Acid Sequence
Animals
Genetic Variation
Humans
Molecular Sequence Data
Receptors, Antigen, T-Cell, alpha-beta
Sequence Alignment
T-Lymphocytes
T-Lymphocytes, Cytotoxic
T-Lymphocytes, Helper-Inducer

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.