Article
Two tandemly organized human genes encoding the T-cell gamma constant-region sequences show multiple rearrangement in different T-cell types.
Nature - 1 Jan 2000
Lefranc M P, Rabbitts T H
Abstract excerpt
The recent detailed analysis of genes that undergo rearrangement in T cells has shown that the T-cell receptor genes encoding alpha- and beta-chains are involved in specific alterations in T-cell DNA analogous to the immunoglobulin genes. A third type of gene, designated gamma, has been isolated...
Topics
- Amino Acid Sequence
- Base Sequence
- Cell Line
- DNA Restriction Enzymes
- Genes
- Humans
- Immunoglobulin Constant Regions
- Immunoglobulin Heavy Chains
- Immunoglobulin gamma-Chains
- Immunoglobulins
- Leukemia
- Nucleic Acid Hybridization
- Phenotype
- T-Lymphocytes