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Article

The ClpP peptidase is the major determinant of bulk protein turnover in Bacillus subtilis.

Journal of bacteriology - 1 Sept 2004

Kock Holger, Gerth Ulf, Hecker Michael

Abstract excerpt

Measurements of overall protein degradation rates in wild-type and clpP mutant Bacillus subtilis cells revealed that stress- or starvation-induced bulk protein turnover depends virtually exclusively on the ClpP peptidase. ClpP is also essential for intracellular protein quality control, and in its absence newly synthesized proteins were highly prone to aggregation even at 37 degrees C. Proteomic comparisons...

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Identifiers

PMID: 15317791
DOI: 10.1128/JB.186.17.5856-5864.2004
PMCID: PMC516825

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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