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Article

The clp proteases of Bacillus subtilis are directly involved in degradation of misfolded proteins.

Journal of bacteriology - 1 Jun 2000

Krüger E, Witt E, Ohlmeier S, Hanschke R, Hecker M

Abstract excerpt

The presence of the heat stress response-related ATPases ClpC and ClpX or the peptidase ClpP in the cell is crucial for tolerance of many forms of stress in Bacillus subtilis. Assays for detection of defects in protein degradation suggest that ClpC, ClpP, and ClpX participate directly in overall proteolysis of misfolded proteins. Turnover rates for abnormal puromycyl peptides are significantly decreased in clpC,...

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Share to ATPases Associated with Diverse Cellular Activities
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Compartmentation

Share to Endopeptidase Clp

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Source

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Identifiers

PMID: 10809708
DOI: 10.1128/JB.182.11.3259-3265.2000
PMCID: PMC94515

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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