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Article

The immune response to hepatitis B vaccine in humans: inheritance patterns in families.

1 Feb 1992

Abstract excerpt

We have recently shown that the human antibody response to the hepatitis B virus surface antigen (HBsAg) vaccine is major histocompatibility complex (MHC) associated. In studies of nonresponders to the vaccine, we found an increased incidence of individuals homozygous for human histocompatibility leukocyte antigen (HLA) proteins associated with the extended (conserved) haplotype [HLA-B8,SC01,DR3]. In later...

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Identifiers

PMID: 1531063
DOI: 10.1084/jem.175.2.495

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