Article
Genetic control of nonresponsiveness to hepatitis B virus vaccine by an extended HLA haplotype.
European journal of immunology - 1 Jul 1992
Hatae K, Kimura A, Okubo R, Watanabe H, Erlich H A, Ueda K, Nishimura Y, Sasazuki T
Abstract excerpt
We previously reported evidence for a statistical association between the serologically determined HLA-Bw54, DR4 and DRw53 alleles and the non-immune responsiveness to hepatitis B virus surface antigen (HBsAg) in the Japanese population. To identify the locus and allele within the HLA region asso...
Topics
- Adult
- Aged
- Alleles
- Complement C4
- Genes, MHC Class I
- Genes, MHC Class II
- HLA-DQ Antigens
- HLA-DR Antigens
- Haplotypes
- Hepatitis B Surface Antigens
- Hepatitis B Vaccines
- Humans
- Middle Aged
- Polymorphism, Restriction Fragment Length
- Viral Hepatitis Vaccines