Article
Genetic control of nonresponsiveness to hepatitis B virus vaccine by an extended HLA haplotype.
European journal of immunology - 1 Jul 1992
Hatae K, Kimura A, Okubo R, Watanabe H, Erlich H A, Ueda K, Nishimura Y, Sasazuki T
Abstract excerpt
We previously reported evidence for a statistical association between the serologically determined HLA-Bw54, DR4 and DRw53 alleles and the non-immune responsiveness to hepatitis B virus surface antigen (HBsAg) in the Japanese population. To identify the locus and allele within the HLA region associated with the nonresponsiveness to HBsAg, serological HLA typing, DNA typing of HLA-DQ and DP alleles using amplified...
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