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Article

Contribution of HLA class I and class II alleles to the regulation of antibody production to hepatitis B surface antigen in humans.

International immunology - 1 Apr 1996

Mineta M, Tanimura M, Tana T, Yssel H, Kashiwagi S, Sasazuki T

Abstract excerpt

The HLA multigene family consists of HLA class I (HLA-A, B and C) and class II (HLA-DR, DQ and DP) genes, and plays a central role in the regulation of immune response. To investigate how each HLA gene and each HLA allele contribute to the human immune response, we immunized 339 healthy Japanese medical students with recombinant hepatitis B surface antigen (rHBsAg) and determined the HLA types of all vaccinated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8671639
DOI: 10.1093/intimm/8.4.525

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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