Article
The exchange factor Cdc24 is required for cell fusion during yeast mating.
Eukaryotic cell - 1 Aug 2004
Barale Sophie, McCusker Derek, Arkowitz Robert A
Abstract excerpt
During Saccharomyces cerevisiae mating, chemotropic growth and cell fusion are critical for zygote formation. Cdc24p, the guanine nucleotide exchange factor for the Cdc42 G protein, is necessary for oriented growth along a pheromone gradient during mating. To understand the functions of this critical Cdc42p activator, we identified additional cdc24 mating mutants. Two mating-specific mutants, the cdc24-m5 and...
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