Article
Disordered cell integrity signaling caused by disruption of the kexB gene in Aspergillus oryzae.
Eukaryotic cell - 1 Aug 2004
Mizutani Osamu, Nojima Akira, Yamamoto Morimasa, Furukawa Kentaro, Fujioka Tomonori, Yamagata Youhei, Abe Keietsu, Nakajima Tasuku
Abstract excerpt
We isolated the kexB gene, which encodes a subtilisin-like processing enzyme, from a filamentous fungus, Aspergillus oryzae. To examine the physiological role of kexB in A. oryzae, we constructed a kexB disruptant (DeltakexB), which formed shrunken colonies with poor generation of conidia on Czapek-Dox (CD) agar plates and hyperbranched mycelia in CD liquid medium. The phenotypes of the DeltakexB strain were...
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