Article
T cell activation following infection of primary follicle center lymphoma B cells with adenovirus encoding CD154.
Leukemia - 1 Sept 2001
Cantwell M J, Wierda W G, Lossos I S, Levy R, Kipps T J
Abstract excerpt
Purified, high-titer adenovirus encoding murine CD154 (Ad-CD154) or human CD154 (Ad-hCD154) was used to infect lymph node cells isolated from patients with follicle center lymphoma. Infection of lymphoma B cells with Ad-CD154 at a multiplicity of infection (MOI) ratio of 100 or higher resulted in high-level transgene expression. Additionally, upon infection of lymphoma B cells, only Ad-CD154 resulted in surface...
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