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Article

p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas.

Molecular cancer therapeutics - 1 Aug 2004

Qin Jian-Zhong, Stennett Lawrence, Bacon Patricia, Bodner Barbara, Hendrix Mary J C, Seftor Richard E B, Seftor Elisabeth A, Margaryan Naira V, Pollock Pamela M, Curtis Amy, Trent Jeffrey M, Bennett Frank, Miele Lucio, Nickoloff Brian J

Abstract excerpt

Once melanoma metastasizes, no effective treatment modalities prolong survival in most patients. This notorious refractoriness to therapy challenges investigators to identify agents that overcome melanoma resistance to apoptosis. Whereas many survival pathways contribute to the death-defying phen...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15299072

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15299072-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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