Article
Diversity of vacA and cagA genes of Helicobacter pylori in Japanese children.
Alimentary pharmacology & therapeutics - 1 Jul 2004
Azuma T, Kato S, Zhou W, Yamazaki S, Yamakawa A, Ohtani M, Fujiwara S, Minoura T, Iinuma K, Kato T
Abstract excerpt
BACKGROUND: Helicobacter pylori infection is generally acquired in childhood and persists as an asymptomatic infection for decades in most infected individuals. Only a minority develops a clinical outcome even in childhood, such as peptic ulcer. It has been reported that H. pylori infection with the type I strain, which expresses the VacA and CagA antigen, is associated with peptic ulcer. AIM: We examined the...
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