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Article

Further characterization of the ts453 mutant of mammalian orthoreovirus serotype 3 and nucleotide sequence of the mutated S4 gene.

Virology - 1 Sept 1992

Danis C, Garzon S, Lemay G

Abstract excerpt

The sigma 3 protein of mammalian orthoreoviruses has multiple proven and postulated roles during viral multiplication. In this manuscript we took advantage of the availability of the ts453 thermosensitive mutant, already assigned to the S4 gene encoding sigma 3, to begin the elucidation of the relationship between the two main domains and the different roles of the sigma 3 viral protein. The alteration in the...

Topics

Base Sequence
Capsid Proteins
Genes, Viral
Microscopy, Electron
Mutation
RNA-Binding Proteins
Reoviridae
Serotyping
Viral Proteins

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1529549
DOI: 10.1016/0042-6822(92)91241-l

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1529549-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Further characterization of the ts453 mutant of mammalian orthoreovirus serotype 3 and nucleotide sequence of the mutated S4 gene.PMID 1529549Read ↗

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