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Article

Smoking influences aberrant CpG hypermethylation of multiple genes in human prostate carcinoma

1 Dec 2005

Abstract excerpt

BACKGROUND: Aberrant CpG methylation profiles of gene promoters and their correlation with advanced pathologic features have been well investigated in prostate carcinoma (PC). Several case-control and prospective studies have revealed a positive association between current smoking and PC. The authors hypothesized that smoking influences both progression and prognosis of PC through CpG hypermethylation of related...

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Share to Epigenetics and DNA Methylation
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PMID: 16323173
DOI: 10.1002/cncr.21577

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