Article
The Burkholderia pseudomallei Proteins BapA and BapC Are Secreted TTSS3 Effectors and BapB Levels Modulate Expression of BopE.
PloS one - 1 Jan 2015
Treerat Puthayalai, Alwis Priyangi, D'Cruze Tanya, Cullinane Meabh, Vadivelu Jamunarani, Devenish Rodney J, Prescott Mark, Adler Ben, Boyce John D
Abstract excerpt
Many Gram-negative pathogens use a type III secretion system (TTSS) for the injection of bacterial effector proteins into host cells. The injected effector proteins play direct roles in modulation of host cell pathways for bacterial benefit. Burkholderia pseudomallei, the causative agent of melioidosis, expresses three different TTSSs. One of these systems, the TTSS3, is essential for escape from host endosomes...
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